Model and Animal Custom Service

Antagene Inc. has secured a 40-acre animal facility with a state-of-the-art animal facility that is UDSA accredited and has NIH Assurance. We are well-positioned as a primary supplier of contract animal research services, providing services to a host of clients. The company is dedicated to offering a wide range of quality preclinical contract animal research services designed to support various research programs. These services range from the preparation of animal models for client use to the complete outsourcing of entire studies.

I. Animal models for research; toxicology; animal nutrition; and intensive systems for the production of animal proteins.

An animal model usually refers to a non-human animal with a disease that is similar to a human condition. These test conditions are often termed as animal models of disease. The use of animal models allows researchers to investigate disease states in ways that would be inaccessible to a human patient.

In order to serve as a useful model, a modeled disease must be similar in etiology (mechanism of cause) and function to the human equivalent. Animal models are used to learn more about a disease, its diagnosis, and its treatment.

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Robust Models

The increase in knowledge about the genomes of non-human primates and other mammals that are genetically close to humans is allowing the production of genetically engineered animal tissues, organs, and even animal species that express human diseases, providing a more robust model of human diseases in an animal model.

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Examples of Our Service

Genetically selected (such as in diabetic mice) animals and customized tissue and toxicology studies.

I. Animal Custom Service:
- Custom Diet Administration
- Animal Aging
- Tumor Modeling and Screening
- Immunization Programs and Test Article

Administration
- Pharmacokinetic/Infusion Administration
- Tissues and Fluids
- Superovulation, Pseudopregant Animals and Special Mating Set Ups

Related Services:
- Molecular Analysis
- Special Breeding Services
- Animal Health Testing

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Animal Histology

Antagene provides research-quality histology services and uses routine paraffin processing, embedding, sectioning, and staining with standard histological methods, including special orientation of tissues, serial and/or step sections, and a range of immunocytochemical analyses. We routinely deal with frozen tissues (both fresh-frozen and fixed-frozen) and sections and stain them for a broad range of biochemical and immunohistochemical stains.

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Service Histology

Description Price
Necropsy [Gross exam and organ harvest] $100 per Mouse
Tissue Trimming and Cassetting - Paraffin $15.0 per cassette
Processing- Paraffin $10.00 per cassette
Embedding- Paraffin $12.00 per cassette
Tissue Trimming and Embedding - Frozen $25.00 per cassette
Std Sectioning- Paraffin $8.00 per slide
Step Sectioning- Paraffin $10.00 per slide
Serial Sectioning- Paraffin $8.00 per slide
Std Sectioning- Frozen $16.00 per slide
Step Sectioning- Frozen $30.00 per slide
Serial Sectioning- Frozen $30.00 per slide
H&E Paraffin $10.00 per slide
H&E Frozen $10.00 per slide
Histopathology Services
Necropsy [Gross exam and organ harvest] $320 per rabbit/$100 per Mouse
Tissue Trimming and Cassetting - Paraffin $15.0 per cassette
Processing- Paraffin $10.00 per cassette
Embedding- Paraffin $12.00 per cassette
Tissue Trimming and Embedding - Frozen $25.00 per cassette
Std Sectioning- Paraffin $8.00 per slide
Step Sectioning- Paraffin $12.00 per slide
Serial Sectioning- Paraffin $8.00 per slide
Std Sectioning- Frozen $16.00 per slide
Step Sectioning- Frozen $30.00 per slide
Serial Sectioning- Frozen $30.00 per slide
H&E Paraffin $10.00 per slide
H&E Frozen $10.00 per slide
Description Price
Histological Staining - Apoptosis
TUNEL Assay- Kit provided by Core $200.00 per slide
Histological Staining - Connective Tissue and Muscle
Gomori's Aldehyde Fuchsin Method [Class II] $100.00/$15.00 per slide
 Gomori's OneStep Trichrome [Class II] $100.00/$15.00 per slide
Histological Staining - Cytoplasmic Granules
Gomori's Method for Pancreatic Islet Cells [Class II] $100.00/$15.00 per slide
Histological Staining - Nerve Cells and Fibers
Luxol Fast Blue [Class III] $200.00/$20.00 per slide
Immunohistochemistry [IHC] Services
Manual IHC - Paraffin $150.00 per slide
Manual IHC - Frozen $150.00 per slide
Automated IHC - Paraffin $120.00 per slide
Automated IHC - Frozen $120.00 per slide
Antibody Optimization
Ab Optimization Type 1 $300.00 per run
Ab Optimization Type 2 $300.00 per run
Ab Optimization Type 3 $600.00 per run
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Animal and Histology Services

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